The terms of the agreement have not been disclosed.
Once closed, the acquisition will build on the work Microsoft is already doing for commercial Windows 10 customers to detect, investigate and respond to advanced attacks on their networks with Windows Defender Advanced Threat Protection (WDATP).
WDATP detects high-profile security cases such as zero-day attacks, ransomware and other advanced cyberthreats.
With the purchase of Hexadite, Microsoft is strengthening its Advanced Threat Protection offering by adding artificial intelligence-based automatic investigation and remediation capabilities.
Following the close of the deal and after a period of integration, Hexadite will be fully absorbed into Microsoft as part of the Windows and Devices Group.
The company is based in Boston with a team of researchers in Tel-Aviv, Israel.